Porphobilinogen, Quantitative, Random Urine
The Porphobilinogen, Quantitative, Random Urine Test measures levels of the porphobilinogen chemical in your urine to help diagnose porphyrias, which are disorders that can cause pain, nervous system issues, and skin problems.
Methodology:
Chromatography/spectrophotometry
Preparation:
No special preparation is required. It is advisable not to use the first voided morning specimen, late evening specimen after 8 PM, or specimen obtained following excessive fluid intake.
Test Results:
3-6 Days. May take longer based on weather, holiday, or lab delays.
Walk-In Lab is prohibited from selling LabCorp tests to residents in the following states:NY, NJ, RI, MA, MD
What is the purpose of this test?
The Porphobilinogen, Quantitative, Random Urine Test measures the amount of a substance called porphobilinogen in your urine. Porphobilinogen is a chemical that is part of the process your body uses to make heme, an important component of hemoglobin in your blood. When there is a problem in this process, it can lead to a build-up of porphobilinogen, which can be a sign of a group of disorders called porphyrias.
Doctors use this test to help diagnose porphyrias, which can cause a variety of symptoms, such as abdominal pain, nervous system issues, and skin problems. By measuring the amount of porphobilinogen in your urine, doctors can determine if you have a porphyria and figure out the best way to treat it. This test is especially useful during an acute attack of porphyria, when symptoms are most severe.
Who should get this test?
A Porphobilinogen, Quantitative, Random Urine Test can benefit individuals who need to check for porphyrias. Here are the groups of people who would benefit from this test:
- People with unexplained abdominal pain: Helps determine if the pain is caused by porphyria.
- People with nervous system symptoms: Such as muscle weakness, numbness, or tingling.
- People with mental health changes: Including confusion, hallucinations, or seizures.
- People with skin problems: Like blisters, itching, or swelling, especially after sun exposure.
- People with a family history of porphyrias: To check if they also have the condition.
- People experiencing an acute attack: To confirm the diagnosis during severe symptoms.
These individuals can benefit from a Porphobilinogen, Quantitative, Random Urine Test to diagnose porphyrias and guide their treatment plan.
When should I order this test?
You should consider ordering a Porphobilinogen, Quantitative, Random Urine Test if you have symptoms that might suggest a porphyria disorder. Here are some symptoms to watch for:
- Severe abdominal pain
- Muscle weakness
- Numbness or tingling
- Mental health changes
- Seizures
- Skin problems
- Dark or reddish urine
If you have these symptoms, talk to your doctor about whether a Porphobilinogen, Quantitative, Random Urine Test is right for you to check for porphyrias and get the correct treatment.
