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Porphyrins Urine Test, Quantitative, 24-Hour

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A Porphyrins Urine Test, Quantitative, 24-Hour is used as follow up if Porphyrins, Quantitative Random Urine comes back abnormal.

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Porphyrins are a group of compounds that are defined by their chemical structure. They are an integral part of certain proteins found in the body such as myoglobin, hemoglobin, and specific enzymes. Porphyrin tests are assays used to help diagnose and monitor a group of disorders called porphyrias. Most porphyrin tests measure and detect the by-products of heme synthesis. Heme, which is an iron-containing pigment, is a part of hemoglobin and a number of other proteins. The synthesis of heme is a step-by-step process that requires the sequential action of 8 different enzymes. If there is a deficiency in one of these enzymes, a bottleneck then forms and precursors (porphyrins such as uroporphyrins, coproporhyrins, and protoporhyrins) build up in the body's fluids and tissues and are excreted in urine and feces. The precursors that build up will depend on where the bottleneck (or enzyme deficiency) is located.

Sample Report

Test Code(s):

003194

Also Known As:

Coproporphyrin, Uroporphyrin

Specimen:

Urine

Preparation:

You must take your lab order to the lab to obtain a proper specimen container before collection. No fasting required. Urinate at 8am and discard the specimen. Then collect all urine in 24-hour period, ending with final collection at 8am the next morning. Refrigerate the collected urine between all voidings or keep it in a cool place. Screw the lid on securely. Transport the specimen promptly to the laboratory. Container must be labeled with full name, date and time collection started, and date and time collection finished.

Test Results:

3-4 days. May take longer based on weather, holiday or lab delays.

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Porphyrins Urine Test, Quantitative, Random

The Porphyrins Urine Test, Quantitative, Random checks for abnormal levels of porphyrins in urine to help diagnose conditions like porphyria, lead poisoning, or skin and nervous system problems.