Gamma-Glutamyl Transferase (GGT) Blood Test

What is the purpose of this test?

The Gamma-Glutamyl Transferase (GGT) Blood Test measures the level of GGT, an enzyme primarily found in the liver, bile ducts, and pancreas. GGT plays a key role in helping the body break down and transport amino acids and other molecules. When the liver or bile ducts become damaged or inflamed, GGT levels often rise, making this test a valuable tool for detecting liver conditions, bile duct issues, or excessive alcohol use. Additionally, the test can help assess overall liver function or monitor the effectiveness of treatment for liver-related conditions.

High GGT levels may suggest liver damage, which can result from alcohol abuse, certain medications, fatty liver disease, hepatitis, or bile duct blockage. Elevated GGT may also indicate pancreatitis, heart disease, or certain types of cancer. Because GGT is highly sensitive to liver changes, it is often used alongside other liver function tests to determine the cause of abnormal results. This test is essential for individuals who show signs of liver damage or those with lifestyle factors that may impact liver health.

Who should get this test?

• Individuals showing symptoms of liver damage or disease.
• People with a history of heavy alcohol use or dependency.
• Individuals taking medications that may affect liver function.
• People with a family history of liver disease or bile duct problems.
• Individuals who have been exposed to chemicals or toxins that may harm the liver.
• Patients being monitored for treatment progress related to liver disease.
• Those experiencing unexplained fatigue, jaundice, or abdominal pain.

When should I order the Gamma-Glutamyl Transferase (GGT) Blood Test?

Individuals may consider ordering this test if they have symptoms or exposure concerns related to liver damage. Symptoms to consider:

• Yellowing of the skin or eyes (jaundice).
• Fatigue or unexplained muscle weakness.
• Nausea, vomiting, or persistent loss of appetite.
• Abdominal pain, swelling, or tenderness.
• Dark urine or pale-colored stools.
• Unexplained weight loss or itchy skin.

If you have these symptoms or suspect liver damage, the Gamma-Glutamyl Transferase (GGT) Blood Test can provide useful information to guide you and your doctor in evaluating your liver health and addressing potential issues.