Tryptase Blood Test

What is the purpose of this test?

The Tryptase Blood Test measures the level of tryptase, an enzyme released by mast cells, in your blood. Mast cells play a key role in allergic reactions and immune system regulation, but elevated tryptase levels can indicate mast cell disorders or severe allergic reactions, such as anaphylaxis. This test is often used to diagnose mastocytosis, a condition where there is an abnormal buildup of mast cells in the body, or to evaluate unexplained allergic symptoms that could point to mast cell activation.

In addition to diagnosing mast cell-related conditions, the Tryptase Blood Test can also help monitor ongoing health issues related to allergies or mast cell dysfunction. By understanding tryptase levels, doctors can create targeted treatment plans and monitor response to therapies. This test is especially valuable for individuals with unexplained symptoms like recurrent flushing, itching, or low blood pressure after allergic triggers.

Who should get this test?

• People experiencing severe allergic reactions, such as anaphylaxis.
• Individuals with unexplained flushing, itching, or hives.
• Those suspected of having mastocytosis or other mast cell disorders.
• Patients with low blood pressure or fainting episodes related to allergic responses.
• Anyone with recurrent or severe allergic symptoms that remain unexplained.

When should I order a Tryptase Blood Test?

Individuals may consider ordering this test if they experience symptoms or have concerns related to mast cell activity or severe allergic reactions. Symptoms to consider:

• Severe allergic reactions with symptoms like difficulty breathing, swelling, or rash.
• Recurring unexplained flushing, itching, or skin irritation.
• Persistent low blood pressure, fainting, or dizziness related to possible allergic triggers.
• Chronic or recurrent anaphylaxis without a clear cause.
• Suspected mastocytosis with symptoms such as abdominal pain, diarrhea, or bone pain.

If you have these symptoms or concerns, the Tryptase Blood Test can help you and your doctor identify or manage potential mast cell-related conditions effectively.