Organic Acids Test - Mosaic Diagnostics Test Kit

What is the purpose of this test?

The Organic Acids Test (OAT) provides a comprehensive overview of an individual’s metabolic health by analyzing 76 different organic acids found in the urine. These acids are byproducts of various biochemical processes in the body, and their levels can indicate potential issues with gut health, energy production, neurotransmitter balance, and detoxification capacity. By evaluating these metabolites, healthcare practitioners can identify imbalances and nutrient deficiencies, guiding a personalized approach to diet and supplementation.

The OAT is a valuable tool for detecting underlying causes of chronic health conditions, especially when symptoms are complex or ambiguous. It helps assess the functional need for essential nutrients, diet modifications, antioxidant support, and other therapies. The test report is organized into categories that cover key areas like gut microbial overgrowth, oxalate metabolism, mitochondrial function, neurotransmitter balance, and more, offering a holistic view of a patient’s health status.

The Organic Acids Test includes the following analytes:

Intestinal Microbial Overgrowth Markers:

• Citramalic Acid
• 5-Hydroxymethyl-2-furoic Acid
• 3-Oxoglutaric Acid
• Furan-2,5-dicarboxylic Acid
• Furancarbonylglycine
• Tartaric Acid
• Arabinose
• Carboxycitric Acid
• Tricarballylic Acid
• 2-Hydroxyphenylacetic Acid
• 4-Hydroxyphenylacetic Acid
• 4-Hydroxybenzoic Acid
• 4-Hydroxyhippuric Acid
• Hippuric Acid
• 3-Indoleacetic Acid
• Succinic Acid
• HPHPA (Clostridia marker)
• 4-Cresol (C. difficile)
• DHPPA (beneficial bacteria)

Oxalate Metabolites:

• Glyceric Acid
• Glycolic Acid
• Oxalic Acid

Glycolytic Cycle Metabolites and Mitochondrial Markers:

• Lactic Acid
• Pyruvic Acid
• 2-Hydroxybutyric Acid
• Fumaric Acid
• Malic Acid
• 2-Oxoglutaric Acid
• Aconitic Acid
• Citric Acid

Neurotransmitter Metabolites:

• Homovanillic Acid (HVA)
• Vanillmandelic Acid (VMA)
• HVA/VMA Ratio
• 5-Hydroxyindoleacetic Acid (5-HIAA)
• Quinolinic Acid
• Kynurenic Acid
• HVA/DOPAC Ratio
• Dihydroxyphenylacetic (DOPAC)

Pyrimidine Metabolites & Ketone and Fatty Acid Oxidation Markers:

• Uracil
• Thymine
• 3-Hydroxybutyric Acid
• Acetoacetic Acid
• 4-Hydroxybutyric Acid
• Ethylmalonic Acid
• Methylsuccinic Acid
• Adipic Acid
• Suberic Acid
• Sebacic Acid
• Methylmalonic Acid (Vitamin B12)

Nutritional Markers:

• Pyridoxic Acid (Vitamin B6)
• Pantothenic Acid (Vitamin B5)
• Glutaric Acid (Vitamin B2-Riboflavin)
• Ascorbic Acid (Vitamin C)
• 3-OH-3-Methylglutaric Acid (Vitamin Q10/CoQ10)
• N-Acetylcysteine (Glutathione precursor and chelating agent)
• Methylcitric Acid (Vitamin H-Biotin)

Indicators of Detoxification:

• Pyroglutamic Acid
• Orotic Acid

Amino Acid Metabolites:

• 2-Hydroxyhippuric Acid
• 2-Hydroxyisovaleric Acid
• 2-Oxoisovaleric Acid
• 3-Methyl-2-oxovaleric Acid
• 2-Hydroxyisocaproic Acid
• 2-Oxoisocaproic Acid
• 2-Oxo-4-methiolbutyric Acid

Additional Markers:

• Mandelic Acid
• Phenyllactic Acid
• Phenylpyruvic Acid
• Homogentisic Acid
• 4-Hydroxyphenyllactic Acid
• N-Acetylaspartic Acid
• Malonic Acid
• 3-Methylglutaric Acid
• 3-Hydroxyglutaric Acid
• 3-Methylglutaconic Acid
• Phosphoric Acid

Who might benefit from the Organic Acids Test?

• Individuals with chronic health conditions that are difficult to diagnose.
• Those experiencing digestive issues or suspected gut imbalances.
• Patients with fatigue, mood disorders, or symptoms of mitochondrial dysfunction.
• People seeking to optimize their nutritional status and overall wellness.
• Individuals with known or suspected exposure to toxins or heavy metals.

Benefits of the Organic Acids Test - Mosaic Diagnostics Test Kit:

• Provides a comprehensive snapshot of metabolic and nutritional health.
• Identifies potential imbalances in gut flora and mitochondrial function.
• Helps detect nutrient deficiencies and oxidative stress markers.
• Guides personalized treatment plans for diet and supplementation.
• Uses a simple, non-invasive urine sample for easy collection at home.