NMR LipoProfile Blood Test

What is the purpose of this test?

The NMR LipoProfile Blood Test uses nuclear magnetic resonance (NMR) technology to measure the number and size of lipoprotein particles in your blood. Unlike standard cholesterol tests that only show the amount of cholesterol present, this test looks deeper at the actual particles that carry cholesterol. These particles can be more accurate indicators of cardiovascular risk, as people with the same cholesterol levels can have different particle counts and sizes, which affect their heart health differently.

This advanced lipid profile helps identify individuals who may appear to have normal cholesterol levels but are still at risk for heart disease due to a higher number of small, dense LDL particles. Small LDL particles can more easily penetrate artery walls and contribute to plaque buildup, increasing the risk of heart attack and stroke. The test also provides information about HDL particles and their size, offering a more complete picture of your cardiovascular health. By identifying these hidden risks, the NMR LipoProfile supports better prevention and treatment strategies.

The NMR LipoProfile Blood Test includes:

• Cholesterol, Total – Measures the total amount of cholesterol in your blood, which includes LDL and HDL cholesterol.
• HDL Cholesterol – Known as "good" cholesterol, it helps remove bad cholesterol from your bloodstream.
• Triglycerides – A type of fat in your blood that can increase the risk of heart disease when elevated.
• LDL Cholesterol (Calc/NIH) – Often called "bad" cholesterol, high levels can lead to plaque buildup in arteries.
• CHOL/HDL-C Ratio – Compares total cholesterol to HDL levels to help assess heart disease risk. (Not Included with LabCorp)
• Non-HDL Cholesterol – Includes all harmful cholesterol types, giving a broader view of risk. (Not Included with LabCorp)
• TG/HDL-C Ratio – Helps evaluate insulin resistance and cardiovascular risk. (Not Included with LabCorp)
• LDL-P – Measures the number of LDL particles; more particles mean a higher heart disease risk.
• Small LDL-P – Measures small, dense LDL particles, which are more dangerous for heart health.
• LDL Size – Indicates whether LDL particles are small (riskier) or large (less risky).
• HDL-P (Total) – Measures the total number of HDL particles, which can help reduce cardiovascular risk.
• Large HDL-P – Large HDL particles are more protective against heart disease. (Not Included with LabCorp)
• HDL Size – Larger HDL particles tend to be more effective at removing cholesterol. (Not Included with LabCorp)
• Large VLDL-P – Measures large, very low-density lipoprotein particles linked to triglyceride levels.(Not Included with LabCorp)
• VLDL Size – Evaluates the size of VLDL particles, which carry triglycerides. (Not Included with LabCorp)
• LDL and HDL Particles – Exclusive to LabCorp, this measurement further breaks down lipoprotein data. (LabCorp Only)

Who should get this test?

• People with a family history of heart disease.
• Individuals with borderline or normal cholesterol levels but high cardiovascular risk factors.
• Those with type 2 diabetes or metabolic syndrome.
• People who have had a heart attack or stroke.
• Individuals looking for a more detailed lipid profile beyond standard cholesterol tests.
• Patients taking cholesterol-lowering medications who want to monitor treatment effectiveness.
• People with high triglyceride levels.

When should I order the NMR LipoProfile Blood Test?

Individuals may consider ordering this test if they have symptoms or concerns related to high cholesterol, heart disease, or metabolic syndrome.

Symptoms to consider:

• Chest pain or pressure, especially during physical activity
• Shortness of breath or fatigue with minimal exertion
• High blood pressure or a known history of cardiovascular issues
• Obesity, especially with excess fat around the waist
• Numbness, coldness, or pain in the extremities
• A family history of heart disease, stroke, or high cholesterol
• Elevated blood sugar levels or insulin resistance
• Difficulty managing cholesterol levels with lifestyle changes or medication

If you have these symptoms or risk factors, the NMR LipoProfile Blood Test can provide more detailed insights into your lipoprotein particle numbers and sizes, which can help guide your doctor in creating a personalized plan to manage your heart health more effectively.