Neuron-specific Enolase (NSE) Blood Test

What is the purpose of this test?

The Neuron-specific Enolase (NSE) Blood Test measures the levels of NSE, a protein found in nerve cells and some types of tumors, especially those linked to neuroendocrine tissues. Elevated levels of NSE can be a sign of certain medical conditions, including small cell lung cancer, neuroblastoma, and other neurological disorders. This test helps doctors monitor these conditions, assess treatment effectiveness, or detect recurrence.

NSE is also used as a marker for brain injury, as it can indicate nerve cell damage in cases like traumatic brain injuries or strokes. By identifying changes in NSE levels, the test can provide vital information for diagnosing and managing these serious conditions, aiding in timely and effective care.

Who should get this test?

• Individuals diagnosed with or being treated for small cell lung cancer or neuroblastoma.
• Those with suspected or confirmed neuroendocrine tumors.
• Patients with symptoms of brain or nerve damage, such as after a head injury or stroke.
• People undergoing treatment for neurological conditions to monitor disease progression or recovery.
• Individuals with unexplained symptoms that may indicate nerve or brain injury.

When should I order a Neuron-specific Enolase (NSE) Blood Test?

Individuals may consider ordering this test if they have symptoms or concerns related to nerve or brain damage, or specific types of tumors. Symptoms to consider:

• Persistent or worsening headaches, confusion, or difficulty thinking clearly.
• Sudden weakness, loss of coordination, or numbness in the body.
• Unexplained fatigue, weight loss, or lumps that may suggest a tumor.
• Ongoing neurological symptoms like memory loss or seizures.
• Symptoms of stroke, such as difficulty speaking or drooping on one side of the face.

If you have these symptoms or are monitoring a known condition, the Neuron-specific Enolase (NSE) Blood Test can provide important insights to guide you and your doctor in making informed decisions about your health.