What is the purpose of this test?
As part of the Gut Pathogen Profile, you have the option to add on Potassium Hydroxide (KOH) Preparation. This microscopic evaluation can detect all types of yeast, regardless of their viability. Please note that this add-on is only available with other GI stool profiles.
KOH, or potassium hydroxide, is a potent alkaline substance that clears cellular material and enhances fungal elements' visibility. Results are reported as the amount of yeast detected microscopically:
- Rare: 1-2 per slide
- Few: 2-5 per high power field (HPF)
- Moderate: 5-10 per HPF
- Many: >10 per HPF
Typically, the yeasts that are identified through culture are the ones that are isolated. If there is a negative yeast culture, it means that the microscopic yeast reflects organisms that are not strong enough to grow in the culture. The presence of yeast on the KOH prep should be compared with the patient's symptoms. If there is moderate yeast, it may indicate overgrowth.
Individuals should note that although this test is included as part of the Gut Pathogen Profile (GD2207), it is only offered as an add-on test for the following Genova Diagnostics test kits:
- Gastrointestinal (GI) Effects Comprehensive Stool Profile 1-Day Test Kit (GD2200)
- Gastrointestinal (GI) Effects Comprehensive Stool Profile 3-Day Test Kit (GD2201)
- Gastrointestinal (GI) Effects Microbial Ecology Stool Profile (GD2205)
- Gastrointestinal (GI) Effects Fundamentals Stool Profile (GD2209)
Don't hesitate to contact Walk-In Lab's Customer Service at 1-800-539-6119 if you are interested in this add-on test, as additional charges will be applied.
Preparation:
Ship test kits to the lab Monday-Thursday only. No fasting is required for collection. However, before collecting a sample for fat absorption assessment, patients should consume their normal dietary fat intake. It is recommended to wait at least two weeks after completing medications such as PPIs, bismuth, antifungals, antibiotics, probiotics, and anti-parasitics. Patients should avoid taking digestive enzymes, laxatives (particularly mineral or castor oil), antacids, aspirin, and substances containing barium or bismuth for at least 48 hours before and during specimen collection. Consult with your physician before stopping any medications.
Test Results:
14 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.