What is the purpose of this test?
The Insulin-Like Growth Factor-Binding Protein 3 (IGFBP-3) Blood Test is a diagnostic tool that measures the level of IGFBP-3 in the blood. IGFBP-3 is a protein that binds to Insulin-Like Growth Factor (IGF), a hormone that plays a crucial role in regulating cell growth and division. The test is usually ordered in conjunction with other tests to evaluate growth and development issues, such as short stature, delayed puberty, and acromegaly. In children with short stature, low levels of IGFBP-3 can indicate growth hormone deficiency, while high levels can suggest an overproduction of growth hormone. In adults with acromegaly (a condition in which the body produces too much growth hormone), IGFBP-3 levels may be elevated.
The IGFBP-3 Blood Test can also be used to monitor the effectiveness of treatment for certain types of cancer, such as prostate, breast, and lung cancer. In these cases, IGFBP-3 levels can help predict whether the cancer will respond to treatment or recur after treatment.
Moreover, the test can be used to diagnose or monitor conditions related to growth hormone deficiency, such as pituitary gland tumors. It can also be used to assess the risk of developing metabolic disorders, such as diabetes, as low levels of IGFBP-3 have been associated with an increased risk of type 2 diabetes. Overall, the IGFBP-3 Blood Test is a valuable tool for diagnosing and monitoring a variety of conditions related to growth and development, cancer, and metabolic disorders.
Who benefits from this test?
The IGFBP-3 Blood Test is beneficial to:
- Patients with growth hormone deficiency
- Individuals with short stature or delayed growth
- People with suspected acromegaly or gigantism
- Those with suspected insulin resistance or type 2 diabetes
- Individuals with suspected osteoporosis or bone growth disorders
- Patients with liver disease or chronic kidney disease
- Athletes or bodybuilders who want to monitor their growth hormone levels
- Individuals undergoing cancer treatment or with a history of cancer
- Those with pituitary gland disorders
When should I order an IGFBP-3 Blood Test?
An IGFBP-3 blood test may be ordered if you are experiencing the following symptoms:
- Short stature or delayed growth in children
- Increased muscle weakness
- Unexplained weight gain or loss
- Fatigue or weakness
- Difficulty concentrating or memory problems
- Bone pain or fractures
- Early or delayed puberty
- Excessive thirst or urination
It's important to note that this is not an exhaustive list, and other factors may also warrant an IGFBP-3 blood test. It's always best to consult with a healthcare provider if you have any concerns about your health.
LC Sample ReportQD Sample Report
Test Code(s):
140152, 34458
Preparation:
No special preparation is required.
Test Results:
3-4 days. May take longer based on weather, holiday, or lab delays.
