Estrogen #2 Essential Blood Test Panel

Quick Facts

• Sample: Blood
• Fasting: No fasting required. Stop biotin consumption at least 72 hours prior to the collection. No isotopes administered 24 hours prior to venipuncture. Patient must avoid having radioisotope scan prior to collection of specimen.
• Turnaround: 4-7 business days. May take longer based on weather, holiday, or lab delays.

What's Included

Estrogens, Total

• Estrogens, Total: The combined concentration of estrogens in the blood, primarily estradiol, estrone, and estriol, which help regulate reproductive function, menstrual cycles, and bone health.

Estrone, Serum (E1)

• Estrone: The primary form of estrogen after menopause, produced mainly through the conversion of other hormones in fat tissue and other peripheral tissues. Helps support reproductive function and bone health.

Estradiol (E2)

• Estradiol: The primary form of estrogen during the reproductive years, produced mainly by the ovaries and in smaller amounts by the testes and other tissues. Helps regulate reproductive function, menstrual cycles, and bone health.

Estriol, Serum (E3)

• Estriol: A form of estrogen that increases significantly during pregnancy, produced primarily by the placenta using precursors from the fetus. Helps support pregnancy and fetal development.

Follicle-Stimulating Hormone (FSH)

• Follicle-Stimulating Hormone (FSH): A hormone produced by the pituitary gland that stimulates ovarian follicle development and estrogen production in women and supports sperm production in men.

Luteinizing Hormone (LH)

• Luteinizing Hormone (LH): A hormone produced by the pituitary gland that triggers ovulation and supports progesterone production in women and stimulates testosterone production in men.

Benefits

• Reviews total estrogens alongside estrone, estradiol, and estriol in one panel.
• Shows individual estrogen fractions, not just an overall estrogen value.
• Includes estradiol, which relates to ovulation, conception, and bone structure in women.
• Includes estriol, the estrogen that rises during pregnancy.
• Gives you a detailed estrogen snapshot to review with your healthcare provider.

Who Is This Test For?

• Women who want a closer look at estrogen levels around menopause.
• Women interested in estradiol, which supports ovulation and the menstrual cycle.
• Pregnant individuals curious about estriol, the major estrogen of pregnancy.
• Men who want to check estradiol, made by the testes and adrenal glands.
• Anyone who wants individual estrogen fractions rather than a single overall value.

How It Works

1. Order Your Test Online
2. Visit a Local Lab
3. Get Results Online

FAQ

1. Do I need to fast or prepare for this test?

No fasting required. Stop biotin consumption at least 72 hours prior to the collection. No isotopes administered 24 hours prior to venipuncture. Patient must avoid having radioisotope scan prior to collection of specimen.

2. How quickly will I get results?

Expect results in 4-7 business days. May take longer based on weather, holiday, or lab delays.

3. What can my results tell me?

Together, these four measurements give you both the big picture and the details of your estrogen levels. One result reflects estrogens overall, while the other three show how individual estrogen fractions contribute. Reviewing them side by side helps you and your provider see where your estrogen profile stands at the time of your blood draw.

4. How do the tests in this panel differ from one another?

Each measurement plays a distinct role. Estrogens, Total gives an overall estrogen reading. Estrone (E1) is the major estrogen after menopause and is often made in fat tissue. Estradiol (E2) is made mainly in the ovary in women, and by the testes and adrenal glands in men. Estriol (E3) is the major estrogen in pregnancy and is produced largely in the placenta. They are not interchangeable.

5. How do I interpret the results?

Look for patterns rather than a single number. Each marker offers a different type of information, so one value read alone can be misleading, and the values need not all move in the same direction. Symptoms, medical history, medications, and other lab findings all shape what your results mean. Your healthcare provider can put them in context.

Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.

6. What should I do if my results are abnormal?

Start by sharing your results with a qualified healthcare provider. An out-of-range value does not diagnose a condition or automatically call for treatment. Your provider can look at your results as a whole, consider your health history, and decide whether any further evaluation makes sense. Please do not make changes to your medications based on results alone.

Pre-test preparation

No fasting is required. Stop biotin consumption at least 72 hours before collection. Avoid isotope administration for 24 hours before blood collection and do not undergo a radioisotope scan before specimen collection.