Quick Facts
- Sample: Blood
- Fasting: No fasting is required. Stop biotin consumption at least 72 hours before collection. Avoid isotope administration for 24 hours before blood collection, and do not undergo a radioisotope scan before specimen collection.
- Turnaround: 4-7 business days. May take longer based on weather, holiday, or lab delays.
What's Included
Estradiol (E2)
Estradiol: The primary form of estrogen during the reproductive years, produced mainly by the ovaries and in smaller amounts by the testes and other tissues. Helps regulate reproductive function, menstrual cycles, and bone health.
Estrone, Serum (E1)
Estriol, Serum (E3)
Estrogens, Total
Estrogens, Total: The combined concentration of estrogens in the blood, primarily estradiol, estrone, and estriol, which help regulate reproductive function, menstrual cycles, and bone health.
Benefits
- Measures estradiol, estrone, and estriol alongside total estrogens in one blood draw.
- Shows how different estrogen types appear in your blood.
- Gives hormone level information to review with your healthcare provider.
- Includes estradiol, which supports ovulation, conception, and pregnancy in women.
- Includes estrone, the major estrogen after menopause.
Who Is This Test For?
- You want a baseline look at your estrogen hormone levels.
- You want to check for hormone imbalances that might affect your health.
- You are postmenopausal and want estrone measured.
- You are pregnant and want estriol, the major estrogen in pregnancy, measured.
- You are male and want to check estradiol, since small amounts of estrogen are found in males.
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. Do I need to fast or prepare for this test?
No fasting is required. Stop biotin consumption at least 72 hours prior to the collection. No isotopes should be administered 24 hours prior to venipuncture. Avoid having a radioisotope scan prior to collection of your specimen.
2. How quickly will I get results?
Expect results in 4-7 business days. May take longer based on weather, holiday, or lab delays.
3. What can my results tell me?
Four measurements work side by side here: estradiol, estrone, estriol, and total estrogens. Looking at individual estrogen types next to the overall total gives a broader hormone picture than any single number. Doctors can use that picture to understand your hormone levels and check for imbalances that might affect health.
4. How do the tests in this panel differ from one another?
Each estrogen has its own source and setting. Estradiol is made mainly in the ovaries in women, and in men by the testes and adrenal glands. Estrone is the major estrogen after menopause and comes from adrenal metabolites and fat tissue. Estriol is the major estrogen in pregnancy, produced largely in the placenta. Total estrogens reflects the group as a whole rather than one hormone.
5. How do I interpret the results?
Meaning comes from the pattern across all four values, not from a single number. Each estrogen reflects something different, so values need not move together. Context matters too, including your symptoms, medical history, menopausal or pregnancy status, and following the preparation steps. Estriol also varies naturally from day to day, so each reading is a snapshot. Review your report with a qualified healthcare provider.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
6. What should I do if my results are abnormal?
Start by sharing your report with a qualified healthcare provider. One out-of-range value does not tell the whole story, and patterns across several results often need clinical interpretation. Your provider can explain what your numbers mean for you and decide whether any further evaluation makes sense.
Pre-test preparation
No fasting is required. Stop biotin consumption at least 72 hours before collection. Avoid isotope administration for 24 hours before blood collection, and do not undergo a radioisotope scan before specimen collection.
