Chaetomium Globosum IgE Blood Test

This test measures the IgE antibody levels to screen for and diagnose an allergy to Chaetomium Globosum (C. globosum) mold. C. globosum is a hydrophilic (water-loving) mold belonging to the Chaetomiaceae family. This mold is commonly found in moist soil, compost, and plant debris. C. globosum may also be found in other moist areas, including:

• Carpets
• Ceiling tiles
• Drywall
• Fabrics
• Insulation
• Leaks in roofs, windows, or pipes
• Paint
• Solid or manufactured wood
• Wallpaper
• Water-damaged building materials

C. globosum is found both indoors and outdoors. C. globosum can often infiltrate homes through open doors, windows, vents, and heating and air conditioning systems. Mold spores in the air outside can also attach themselves to clothing, shoes, and pets and can be carried indoors. Since this mold is water-loving, it thrives in warm, humid environments by dissolving into the water in the air or on surfaces. Individuals living in these environments may inhale these mold spores and develop an allergy to C. globosum.

A C. globosum allergy activates a response in an individual's immune system upon inhalation of the allergen. Once the mold spores come in contact with the airways, the immune system will view them as harmful and produce antibodies to combat these invaders. Unfortunately, these antibodies cause a chemical called histamine to be released, triggering an allergic reaction.

The allergic reaction may range from mild or moderate to severe and vary for each individual. An individual may experience allergic reactions minutes to a few hours after exposure to mold spores. An individual with an allergy to C. globosum may experience hay fever or asthma-like symptoms, such as:

• Congestion
• Hives
• Itching
• Red or watery eyes
• Lightheadedness
• Runny nose
• Sneezing
• Sore Throat
• Swelling
• Trouble breathing or wheezing

An extreme, potentially life-threatening allergic reaction known as anaphylaxis may occur in the most severe cases. An anaphylactic response requires immediate medical attention. Signs or symptoms of anaphylaxis may include:

• Rapid or increased pulse
• Swollen throat or lump making it difficult to breathe
• Low blood pressure
• Extreme dizziness or loss of consciousness