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C-Telopeptide Blood Test (Endocrine Sciences)

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The C-Telopeptide (CTX) Blood Test measures CTX levels in the blood, aiding in diagnosing and monitoring conditions affecting bone health, such as osteoporosis and bone fractures.

LabCorp

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Test Code:

500089

CPT Code(s):

82523

Also Known As:

Type 1 Collagen, C-Telopeptide

Methodology:

Electrochemiluminescence Immunoassay (ECLIA)

Specimen:

Blood

Preparation:

Fasting for at least 10-12 hours is required. Patients should stop biotin consumption at least 72 hours prior to the collection.

Test Results:

4-8 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling LabCorp tests to residents in the following states:NY, NJ, RI, MA, MD

Quest

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Sample Report Compare
Test Code:

17406

CPT Code(s):

82523

Also Known As:

Type 1 Collagen, C-Telopeptide

Methodology:

Immunoassay (IA)

Specimen:

Blood

Preparation:

Fasting for at least 10-12 hours is required. Patients should stop biotin consumption at least 72 hours prior to the collection.

Test Results:

4-6 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI


What is the purpose of this test?

The C-Telopeptide (CTX) Blood Test is a diagnostic tool used to measure the level of a protein fragment called collagen type 1 cross-linked C-telopeptide in the blood. This protein is released when bones break down, so the CTX test is primarily used to detect bone loss or monitor treatment for osteoporosis. Osteoporosis is a condition where bones become weak and brittle, making them more likely to break. The condition is most commonly seen in postmenopausal women but can also affect men and younger women. 

The CTX test is particularly useful as it can detect bone loss early, before it leads to osteoporosis. The test can also help to monitor the effectiveness of treatment for osteoporosis, such as lifestyle changes, medications or supplements. Additionally, the CTX test can be used to detect bone metastasis or spread of cancer to the bones, which can help to guide appropriate treatment. 

The CTX test is generally ordered by a doctor if they suspect the patient has bone loss or risk factors for osteoporosis. These risk factors may include a personal or family history of osteoporosis, low body weight, smoking, excessive alcohol consumption, or long-term use of certain medications like steroids. The test is performed on a blood sample, which is usually taken from a vein in the arm. The test results can provide valuable information about a patient's bone health and guide appropriate treatment options.

Who would benefit from this test?

The C-Telopeptide Blood Test would be beneficial to:

  • Individuals with osteoporosis or at risk for osteoporosis.
  • Individuals with bone metastases or suspected bone metastases.
  • Individuals undergoing treatment for bone-related disorders.
  • Individuals with a family history of bone-related disorders.
  • Individuals with chronic kidney disease.
  • Individuals with hyperparathyroidism.
  • Individuals with a history of fractures or bone injuries.

When should I order a C-Telopeptide Blood Test?

A C-Telopeptide blood test is usually ordered to assess bone health and to diagnose conditions such as osteoporosis. Here are some symptoms that may indicate the need for a C-Telopeptide blood test:

  • Frequent bone fractures
  • Chronic back pain
  • Joint pain and stiffness
  • Unexplained loss of height
  • A family history of osteoporosis or bone fractures
  • Menopause
  • Long-term use of corticosteroid medications

If you are experiencing any of these symptoms or have any concerns about your bone health, it is best to consult with your healthcare provider who can evaluate your condition and determine if a C-Telopeptide blood test is necessary.

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