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Beta-2 Microglobulin, Urine Test

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The Beta-2 Microglobulin, Urine Test measures a protein in urine to check for kidney problems, helping doctors detect early kidney damage in conditions like multiple myeloma or chronic infections.

LabCorp

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Test Code:

010173

CPT Code(s):

82232

Methodology:

Immunochemiluminometric assay (ICMA)

Specimen:

Urine

Preparation:

No special preparation is required.

Test Results:

3 - 4 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling LabCorp tests to residents in the following states:NY, NJ, RI, MA, MD


What is the purpose of this test?

The Beta-2 Microglobulin (B2M) Urine Test is used to measure the level of a protein called beta-2 microglobulin in urine. This protein is found in most cells in the body, but higher levels in the urine can indicate problems with the kidneys. The kidneys are responsible for filtering waste and extra fluids from the blood, and when they are damaged or not working properly, beta-2 microglobulin can leak into the urine. By measuring the amount of this protein, doctors can assess how well the kidneys are functioning.

Doctors might order a B2M Urine Test if they suspect kidney disease or want to monitor the kidney function of someone with a known kidney condition. This test can also help detect early kidney damage in people with certain conditions like multiple myeloma or chronic infections. By identifying kidney problems early, doctors can provide treatment to prevent further damage and manage the condition more effectively.

Who should get this test?

The Beta-2 Microglobulin, Urine Test would be beneficial to:

  • People with suspected kidney disease.
  • Individuals with known kidney conditions.
  • Patients with multiple myeloma.
  • People with chronic infections.
  • Individuals undergoing treatment that might affect kidney function.
  • Patients with autoimmune diseases affecting the kidneys.

When should I order a Beta-2 Microglobulin, Urine Test?

Individuals should consider ordering a Beta-2 Microglobulin (B2M) Urine Test if they suspect kidney problems or need to monitor kidney function. Here are some specific situations and symptoms to look for:

  • Suspected Kidney Disease
    • Persistent fatigue
    • Swelling in the legs, ankles, or feet
    • Decreased urine output
    • Foamy urine
  • Known Kidney Conditions
    • Monitoring the progression or effectiveness of treatment
  • Multiple Myeloma
    • Bone pain
    • Frequent infections
    • Unexplained weight loss
  • Chronic Infections
    • Recurrent fevers
    • Persistent infections that don’t respond well to treatment
  • Symptoms Indicating Kidney Issues
    • High blood pressure
    • Blood in the urine
    • Pain in the lower back or sides
    • Nausea and vomiting
    • Loss of appetite

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