Amylase Urine Test

What is the purpose of this test?

Order this Amylase Urine Test, which is used to diagnose and monitor pancreatitis and other pancreatic diseases using a random or timed urine specimen. Amylase is an enzyme that aids in the digestion of carbohydrates. It's made by the pancreas and salivary glands. The pancreas is a narrow, flat organ located deep in the abdomen, below the liver, and between the stomach and spine. Digestive enzymes are made by the pancreas and sent into the pancreatic duct through small tubes. Amylase is released through the pancreatic duct into the small intestine, where it breaks down dietary carbohydrates. Normally, only small amounts of amylase are found in urine. But if cells in the pancreas are injured, more amylase is released into the blood and urine. This can happen with pancreatitis, inflammation of the pancreas, or when a gallstone or pancreatic tumor blocks the pancreatic duct.

Healthcare providers often use a urine amylase test to detect pancreatic diseases and monitor kidney function. Normally, the amylase level in urine reflects the amylase level in the blood, but the increase and decrease happen later. Occasionally, a urine creatinine test and urine amylase test are also requested. The ratio between amylase and creatinine can be computed to evaluate the health of the kidneys.

When should I order an Amylase Urine Test?

Individuals may order this test if they have experienced symptoms of a pancreatic disorder, such as:

• Intense upper abdominal pain that radiates to the back or feels worse after eating
• Fever
• Loss of appetite
• Nausea or vomiting
• Jaundice
• Rapid pulse
• Loose, fatty, foul-smelling stools (steatorrhea)